The goal of the Diindolylmethane Information Resource Center is to provide an accurate scientific summary of Diindolylmethane DIM for consumers and biomedical investigators. It is a collaborative initiative of faculty members and research fellows at the University of California at Berkeley. Diindolylmethane has a molecular weight of and is pale yellow in crystalline form. The purified compound does not have any taste. Diindolylmethane is a lipophilic oil-soluble compound. Similar to other oil-soluble phytochemicals, such as lycopene and lutein, the presence of vegetable oil and other lipophilic compounds, such as phosphatidylcholine, that aid in the formation of absorption micelles within the gastrointestinal tract, greatly increase the bioavailability of DIM upon oral administration. Most of the preclinical animal studies and some of the human clinical trials conducted with DIM have consisted of DIM co-administered with vegetable oils. Some of the formulations have additionally contained phosphatidylcholine and other lipophilic excipients for enhanced absorption. When formulated correctly, Diindolylmethane is a highly bioavailable compound.
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